All Phenotypes Akr1c13<em1Jjwo> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Akr1c13^em1Jjwo
endonuclease-mediated mutation 1, Joshua J Woodward
MGI:8395685

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Akr1c13^em1Jjwo/Akr1c13^em1Jjwo	C57BL/6J-Akr1c13^em1Jjwo	MGI:8395687

Allelic Composition	Akr1c13^em1Jjwo/Akr1c13^em1Jjwo
Genetic Background	C57BL/6J-Akr1c13^em1Jjwo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Akr1c13^em1Jjwo mutation (0 available); any Akr1c13 mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

decreased susceptibility to bacterial infection induced morbidity/mortality ( J:389353 )

• mice exhibit increased survival to L. monocytogenes infection

immune system

decreased susceptibility to bacterial infection ( J:389353 )

• mice show reduced bacterial burden when infected with Listeria monocytogenes by intraperitoneal injection or intravenous route and are resistant to acute high-dose infection via intravenous route with Listeria monocytogenes

decreased susceptibility to bacterial infection induced morbidity/mortality ( J:389353 )

• mice exhibit increased survival to L. monocytogenes infection

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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