Phenotypes associated with this allele

• Allele Symbol: Nrxn3^em1Hssh
• Allele Name: endonuclease-mediated mutation 1, Hee-Sup Shin
• Allele ID: MGI:8395562
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nrxn3^em1Hssh/Nrxn3^em1Hssh	C57BL/6J-Nrxn3^em1Hssh	MGI:8395591

Genotype
MGI:8395591

hm1

• Allelic Composition: Nrxn3^em1Hssh/Nrxn3^em1Hssh
• Genetic Background: C57BL/6J-Nrxn3^em1Hssh

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:269348 )

N • normal behavior in standard fear conditioning and 24-h contextual fear memory

N • normal 24-h memory

increased fear-related response ( J:269348 )

• in observational fear task, where observer mouse that doesnt receive direct aversive stimuli is conditioned for context-dependent fear by observing a demonstrator mouse receiving repetitive foot shocks, the subject (observer) mouse displays fear when placed in the same environment without the demonstrator mouse