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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Thrbem1Lmoe
endonuclease-mediated mutation 1, Lars C Moeller
MGI:8394035
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Thrbem1Lmoe/Thrbem1Lmoe involves: C57BL/6J MGI:8394325
cx2
 		Thratm2Jas/Thratm2Jas
Thrbem1Lmoe/Thrbem1Lmoe 		involves: 129 * C57BL/6J MGI:8394331


Genotype
MGI:8394325
hm1
Allelic
Composition		 Thrbem1Lmoe/Thrbem1Lmoe
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Thrbem1Lmoe mutation (0 available); any Thrb mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:253749 )
N
• normal food intake

homeostasis/metabolism
homeostasis/metabolism phenotype ( J:253749 )
N
• normal hypoglycemic effect of active thyroid hormone (T3) injection
• normal circulating cholesterol, albumin and total protein levels
• normal blood and liver triglyceride levels




Genotype
MGI:8394331
cx2
Allelic
Composition		 Thratm2Jas/Thratm2Jas
Thrbem1Lmoe/Thrbem1Lmoe
Genetic
Background		 involves: 129 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Thratm2Jas mutation (1 available); any Thra mutation (40 available)
Thrbem1Lmoe mutation (0 available); any Thrb mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/14/2026
MGI 6.24 		The Jackson Laboratory