Phenotypes associated with this allele

• Allele Symbol: Ajap1^em1Bet
• Allele Name: endonuclease-mediated mutation 1, Bernhard Bettler
• Allele ID: MGI:8377433
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Ajap1^em1Bet/Ajap1^+	C57BL/6J-Ajap1^em1Bet	MGI:8378126

Genotype
MGI:8378126

ht1

• Allelic Composition: Ajap1^em1Bet/Ajap1⁺
• Genetic Background: C57BL/6J-Ajap1^em1Bet

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

increased excitatory postsynaptic current amplitude ( J:388888 )

• reduced baclofen-induced sEPSC amplitude inhibition

increased excitatory postsynaptic current frequency ( J:388888 )

• reduced baclofen-induced sEPSC frequency inhibition

abnormal excitatory postsynaptic potential ( J:388888 )

• shallower fEPSP slope after theta-burst stimulation (TBS)

abnormal inhibitory postsynaptic currents ( J:388888 )

• reduced baclofen-induced sIPSC frequency inhibition

increased inhibitory postsynaptic current amplitude ( J:388888 )

• reduced baclofen-induced sIPSC amplitude inhibition

reduced long-term potentiation ( J:388888 )

• after theta-burst stimulation (TBS)