Phenotypes associated with this allele

• Allele Symbol: Plau^em1Elne
• Allele Name: endonuclease-mediated mutation 1, Elena Neyfeld
• Allele ID: MGI:8348312
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plau^em1Elne/Plau^em1Elne	C57BL/6J-Plau^em1Elne	MGI:8348349

Genotype
MGI:8348349

hm1

• Allelic Composition: Plau^em1Elne/Plau^em1Elne
• Genetic Background: C57BL/6J-Plau^em1Elne

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:386319 )

N • normal locomotion

abnormal cognition ( J:386319 )

• reduced latency and increased success rate in finding a way to escape in extrapolation escape test

increased aggression towards mice ( J:386319 )

increased thigmotaxis ( J:386319 )

• less time spent in open arms and center in elevated plus maze test

decreased social novelty preference ( J:386319 )

• less time spent with novel mouse

social withdrawal ( J:386319 )

• less time spent with familiar and unfamiliar mice, preferring isolation