About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Prm1-Fbxo24)FLAGOsb
transgene insertion FLAG, Research Institute for Microbial Diseases, Osaka University
MGI:8348264
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Fbxo24em1Osb/Fbxo24em1Osb
Tg(Prm1-Fbxo24)FLAGOsb/0 		involves: C57BL/6NJcl * DBA/2NJcl MGI:8363262


Genotype
MGI:8363262
cx1
Allelic
Composition		 Fbxo24em1Osb/Fbxo24em1Osb
Tg(Prm1-Fbxo24)FLAGOsb/0
Genetic
Background		 involves: C57BL/6NJcl * DBA/2NJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxo24em1Osb mutation (0 available); any Fbxo24 mutation (82 available)
Tg(Prm1-Fbxo24)FLAGOsb mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal sperm flagellum morphology ( J:366671 )
• cauda epididymal spermatozoa exhibit bent or coiled flagella, indicating that the transgene fails to rescue the sperm morphology seen in males homozygous for the Fbxo24em1Osb allele; this is likely due to lower expression of FBXO24 and/or FLAG-tag interfering with FBXO24

cellular
abnormal sperm flagellum morphology ( J:366671 )
• cauda epididymal spermatozoa exhibit bent or coiled flagella, indicating that the transgene fails to rescue the sperm morphology seen in males homozygous for the Fbxo24em1Osb allele; this is likely due to lower expression of FBXO24 and/or FLAG-tag interfering with FBXO24




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/09/2026
MGI 6.24 		The Jackson Laboratory