Phenotypes associated with this allele

• Allele Symbol: Men1^em1Jiez
• Allele Name: endonuclease-mediated mutation 1, Jie Zhang
• Allele ID: MGI:8317011
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Men1^em1Jiez/Men1^em1Jiez	C57BL/6-Men1^em1Jiez	MGI:8317023

Genotype
MGI:8317023

hm1

• Allelic Composition: Men1^em1Jiez/Men1^em1Jiez
• Genetic Background: C57BL/6-Men1^em1Jiez

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:379428 )

N • normal behavior in rotarod, open field, elevated plus maze, T/Y maze and Morris water maze tests

abnormal sucrose solution preference ( J:379428 )

• decreased preference

behavioral despair ( J:379428 )

• longer immobility (freezing) in forced swim test and tail suspension test

growth/size/body

growth/size/body region phenotype ( J:379428 )

N • normal growth

mortality/aging

mortality/aging ( J:379428 )

N • normal lifespan

nervous system

nervous system phenotype ( J:379428 )

N • normal brain morphology and size

decreased miniature excitatory postsynaptic current frequency ( J:379428 )

• in brain neurons

increased miniature inhibitory postsynaptic current frequency ( J:379428 )

• in brain neurons