Phenotypes associated with this allele

• Allele Symbol: Epas1^em1.1Zhezh
• Allele Name: endonuclease-mediated mutation 1.1, Zhengping Zhuang
• Allele ID: MGI:8314962
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Epas1^em1.1Zhezh/Epas1^em1.1Zhezh	involves: 129 * C57BL/6 * FVB/N	MGI:8314963

Genotype
MGI:8314963

hm1

• Allelic Composition: Epas1^em1.1Zhezh/Epas1^em1.1Zhezh
• Genetic Background: involves: 129 * C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:380927 )

N • normal white blood cell count at age 2 months

high mean erythrocyte cell number ( J:380927 )

• 40% higher at age 2 months

polycythemia ( J:380927 )

• at age 2 months

increased hematocrit ( J:380927 )

• 57% higher at age 2 months

increased hemoglobin content ( J:380927 )

• 61% higher at age 2 months

increased mean corpuscular volume ( J:380927 )

thrombocytopenia ( J:380927 )

• ~75% lower at age 2 months

homeostasis/metabolism

increased circulating erythropoietin level ( J:380927 )

• approximately 2x higher in plasma