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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dmxl1em1Rstot
endonuclease-mediated mutation 1, Rolf Stottmann
MGI:8293322
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dmxl1em1Rstot/Dmxl1em1Rstot involves: C57BL/6J * C57BL/6NCrl MGI:8296189
ht2
 		Dmxl1em1Rstot/Dmxl1+ involves: C57BL/6J * C57BL/6NCrl MGI:8296190
ht3
 		Dmxl1em1Rstot/Dmxl1em2Rstot involves: C57BL/6J * C57BL/6NCrl MGI:8296196
ht4
 		Dmxl1em1Rstot/Dmxl1em3Rstot Not Specified MGI:8296197


Genotype
MGI:8296189
hm1
Allelic
Composition		 Dmxl1em1Rstot/Dmxl1em1Rstot
Genetic
Background		 involves: C57BL/6J * C57BL/6NCrl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dmxl1em1Rstot mutation (0 available); any Dmxl1 mutation (159 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:376266 )
• all mice die prior to E9.5; no homozygotes can be recovered at any stage from E8.5 to P14




Genotype
MGI:8296190
ht2
Allelic
Composition		 Dmxl1em1Rstot/Dmxl1+
Genetic
Background		 involves: C57BL/6J * C57BL/6NCrl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dmxl1em1Rstot mutation (0 available); any Dmxl1 mutation (159 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:376266 )
• mice are viable and fertile and show normal mandibular length (normalized to body weight) at E18.5




Genotype
MGI:8296196
ht3
Allelic
Composition		 Dmxl1em1Rstot/Dmxl1em2Rstot
Genetic
Background		 involves: C57BL/6J * C57BL/6NCrl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dmxl1em1Rstot mutation (0 available); any Dmxl1 mutation (159 available)
Dmxl1em2Rstot mutation (0 available); any Dmxl1 mutation (159 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:376266 )
• mice are recovered in near Mendelian ratios at P14 with no apparent gross morphological abnormalities and survive normally as adults




Genotype
MGI:8296197
ht4
Allelic
Composition		 Dmxl1em1Rstot/Dmxl1em3Rstot
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dmxl1em1Rstot mutation (0 available); any Dmxl1 mutation (159 available)
Dmxl1em3Rstot mutation (0 available); any Dmxl1 mutation (159 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:376266 )
• mice are recovered in near Mendelian ratios at P14 with no apparent gross morphological abnormalities and survive normally as adults




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory