All Phenotypes Cfap91<em1Osb> MGI Mouse

mortality/aging ( J:377938 )

N	• Background Sensitivity: the number of expected mice are obtained (26.2%) on a mixed 129X1/SvJJmsSlc, C57BL/6NCrSlc and DBA/2CrSlc background unlike on a C57BL/6NCrSlc and DBA/2CrSlc background which shows reduced numbers of mice

oligozoospermia ( J:377938 )

• fewer number of spermatozoa are seen in the cauda epididymis

teratozoospermia ( J:377938 )

• males exhibit oligo-astheno-teratozoospermia

abnormal sperm flagellum morphology ( J:377938 )

• sperm exhibit disrupted flagellum formation

• spermatids show defective microtubule structures

abnormal outer dense fiber morphology ( J:377938 )

• cauda epididymal spermatozoa show abnormalities in the outer dense fiber

abnormal sperm axoneme morphology ( J:377938 )

• cauda epididymal spermatozoa show disordered axoneme structures

abnormal sperm annulus morphology ( J:377938 )

• in cauda epididymal spermatozoa, the annuls does not migrate far enough to the distal region

abnormal sperm mitochondrial sheath morphology ( J:377938 )

• cauda epididymal spermatozoa show abnormalities in mitochondrial sheath

abnormal sperm fibrous sheath morphology ( J:377938 )

• cauda epididymal spermatozoa show abnormalities in the fibrous sheath

short sperm flagellum ( J:377938 )

abnormal sperm head morphology ( J:377938 )

• while morphology of round spermatids is normal, elongating/elongated spermatids and spermatozoa show abnormal head morphology

asthenozoospermia ( J:377938 )

immotile sperm ( J:377938 )

• spermatozoa are completely immotile

decreased testis weight ( J:377938 )

abnormal spermiogenesis ( J:377938 )

• spermiogenesis is defective

small epididymis ( J:377938 )

• males exhibit smaller and lighter epididymis

male infertility ( J:377938 )