Cfap91^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cfap91^em1Osb
• Name: cilia and flagella associated protein 91; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:8280443
• Gene: Cfap91 Location: Chr16:38118116-38162222 bp, - strand Genetic Position: Chr16, 26.71 cM
• Alliance: Cfap91^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NCrSlc x DBA/2CrSlc)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated a 32,204 bp deletion and 4 bp insertion in the genomic region. The deletion was confirmed by genomic PCR. (J:377938)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cfap91 Mutation: 25 strains or lines available

References

• Original: J:377938 Wang H, et al., Proximity labeling of axonemal protein CFAP91 identifies EFCAB5 that regulates sperm motility. Nat Commun. 2025 Sep 10;16(1):8238
• All: 1 reference(s)