Phenotypes associated with this allele

• Allele Symbol: Piezo1^em1Bxiao
• Allele Name: endonuclease-mediated mutation 1, Bailong Xiao
• Allele ID: MGI:8275336
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Piezo1^em1Bxiao/Piezo1^em1Bxiao	C57BL/6-Piezo1^em1Bxiao	MGI:8275753

Genotype
MGI:8275753

hm1

• Allelic Composition: Piezo1^em1Bxiao/Piezo1^em1Bxiao
• Genetic Background: C57BL/6-Piezo1^em1Bxiao

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:360618 )

N • normal feeding and motion

N • normal behavior in open field test

N • normal coordination and balance in rotarod test

impaired exercise endurance ( J:360618 )

• more frequent falls in rotarod endurance test

cardiovascular system

cardiovascular system phenotype ( J:360618 )

N • normal heart rate

increased mean systemic arterial blood pressure ( J:360618 )

• during active period (night)

• normal during rest period (day)

increased systemic arterial systolic blood pressure ( J:360618 )

• during active period (night)

• normal during rest period (day)

growth/size/body

growth/size/body region phenotype ( J:360618 )

N • normal body weight and gross morphology

N • normal organ weight and gross morphology

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:360618 )

N • normal respiration

impaired exercise endurance ( J:360618 )

• more frequent falls in rotarod endurance test

muscle

muscle phenotype ( J:360618 )

N • normal latency to fall in wire hang test