Phenotypes associated with this allele

• Allele Symbol: Prdx1^em1Xixie
• Allele Name: endonuclease-mediated mutation 1, Xiangyang Xie
• Allele ID: MGI:8266888
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prdx1^em1Xixie/Prdx1^em1Xixie	C57BL/6J-Prdx1^em1Xixie	MGI:8266900

Genotype
MGI:8266900

hm1

• Allelic Composition: Prdx1^em1Xixie/Prdx1^em1Xixie
• Genetic Background: C57BL/6J-Prdx1^em1Xixie

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

liver/biliary system

decreased susceptibility to diet-induced hepatic steatosis ( J:363073 )

• reduced liver weight and liver weight to body weight ratio after 20 weeks of Western diet

• reduced liver fibrosis after 20 weeks of Western diet

• decreased alanine aminotransferase (ALT) and aspartate aminotransferase (AST) serum levels

• normal body weight, fat and lean mass to body weight ratios, food intake and energy expenditure after 20 weeks of Western diet