Phenotypes associated with this allele

• Allele Symbol: Scn9a^em1Ics
• Allele Name: endonuclease-mediated mutation 1, Mouse Clinical Institute
• Allele ID: MGI:8266439
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Scn9a^em1Ics/Scn9a^em1Ics	C57BL/6NCrl-Scn9a^em1Ics	MGI:8266440

Genotype
MGI:8266440

hm1

• Allelic Composition: Scn9a^em1Ics/Scn9a^em1Ics
• Genetic Background: C57BL/6NCrl-Scn9a^em1Ics

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal touch/nociception ( J:363988 )

• spontaneous ongoing pain

decreased mechanical nociceptive threshold ( J:363988 )

• in von Frey test

decreased thermal nociceptive threshold ( J:363988 , J:363988 )

• in hot plate, tail flick and thermal preference tests (J:363988)

♂ • increased paw reaction duration in acetone (cooling) test (J:363988)