Phenotypes associated with this allele

• Allele Symbol: Nme3^em1Zefc
• Allele Name: endonuclease-mediated mutation 1, Zee-Fen Chang
• Allele ID: MGI:8264618
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nme3^em1Zefc/Nme3^em1Zefc	involves: C57BL/6J	MGI:8264715

Genotype
MGI:8264715

hm1

• Allelic Composition: Nme3^em1Zefc/Nme3^em1Zefc
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

ataxia ( J:374692 )

• cerebellar ataxia at age 9 months as indicated by the ledge test

• no ataxia at age 2 month as indicated by the ledge test

homeostasis/metabolism

abnormal physiological response to hypoxia ( J:374692 )

• increased area of ischemia-induced cardiac infarction after coronary artery constriction and reperfusion

• normal heart weight

skeleton

kyphosis ( J:374692 )

• hunchback posture at age 9 months in the ledge test