Phenotypes associated with this allele

• Allele Symbol: Ptprk^em1Gne
• Allele Name: endonuclease-mediated mutation 1, Genentech
• Allele ID: MGI:8261383
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ptprk^em1Gne/Ptprk^em1Gne	C57BL/6N-Ptprk^em1Gne	MGI:8261386

Genotype
MGI:8261386

hm1

• Allelic Composition: Ptprk^em1Gne/Ptprk^em1Gne
• Genetic Background: C57BL/6N-Ptprk^em1Gne

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

cataract ( J:353469 )

♂ • in one male mouse

homeostasis/metabolism

increased incidence of tumors by chemical induction ( J:353469 )

♂ • in male mice treated with DSS and AOM that is independent of the catalytic domain

digestive/alimentary system

increased susceptibility to induced colitis ( J:353469 )

♂ • DSS-treated male mice exhibit increased weight loss and shorter colon length than control mice

neoplasm

increased incidence of tumors by chemical induction ( J:353469 )

♂ • in male mice treated with DSS and AOM that is independent of the catalytic domain

reproductive system

reproductive system phenotype ( J:353469 )

N

immune system

increased susceptibility to induced colitis ( J:353469 )

♂ • DSS-treated male mice exhibit increased weight loss and shorter colon length than control mice

growth/size/body

growth/size/body region phenotype ( J:353469 )

N • no statistically significant difference from wild-type mice

increased susceptibility to weight loss ( J:353469 )

♂ • in DSS-treated male mice