Ptprk^em1Gne
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ptprk^em1Gne
• Name: protein tyrosine phosphatase receptor type K; endonuclease-mediated mutation 1, Genentech
• MGI ID: MGI:8261383
• Gene: Ptprk Location: Chr10:27950816-28473393 bp, + strand Genetic Position: Chr10, 15.06 cM
• Alliance: Ptprk^em1Gne page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 1 deleted 22 bp. (J:353469)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptprk Mutation: 126 strains or lines available

References

• Original: J:353469 Young KA, et al., The receptor protein tyrosine phosphatase PTPRK promotes intestinal repair and catalysis-independent tumour suppression. J Cell Sci. 2024 Jul 15;137(14)
• All: 1 reference(s)