Phenotypes associated with this allele

• Allele Symbol: Caprin2^em1Nshi
• Allele Name: endonuclease-mediated mutation 1, Nobuyuki Shiina
• Allele ID: MGI:8254854
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Caprin2^em1Nshi/Caprin2^em1Nshi	involves: C57BL/6J	MGI:8255343

Genotype
MGI:8255343

hm1

• Allelic Composition: Caprin2^em1Nshi/Caprin2^em1Nshi
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal lens morphology ( J:299943 )

• staining of P0.5 eye slices with wheat germ agglutinin indicates a significant reduction in the diameter of the lens nucleus normalized to the total lens diameter

homeostasis/metabolism

abnormal translation ( J:299943 )

• at P0.5, eyes show increased translation of long mRNAs (such as those associated with cell proliferation), whereas the translation efficiency of shorter transcripts that encode lens differentiation factors (such as alpha-, beta-, and gamma-crystallins, lens major intrinsic protein [MIP], CP115, and CP49) is relatively reduced

cellular

abnormal translation ( J:299943 )

• at P0.5, eyes show increased translation of long mRNAs (such as those associated with cell proliferation), whereas the translation efficiency of shorter transcripts that encode lens differentiation factors (such as alpha-, beta-, and gamma-crystallins, lens major intrinsic protein [MIP], CP115, and CP49) is relatively reduced