Allele Symbol Allele Name Allele ID |
Fam171a2em1Yjt endonuclease-mediated mutation 1, Jin-Tai Yu MGI:8187547 |
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Summary |
2 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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• following intrastriatal injection of recombinant alpha-synuclein preformed fibrils loss of TH-positive neurons and fiber degeneration is reduced compared to similarly treated wild-type controls
• performance in behavioral assays (pole test, rotarod test, and wire hang test) following intrastriatal injection of recombinant alpha-synuclein preformed fibrils is similar to wild-type controls
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• reduced accumulation of recombinant alpha-synuclein preformed fibrils following intrastriatal injection compared to similarly treated wild-type controls
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/25/2025 MGI 6.24 |
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