About   Help   FAQ
Fam171a2em1Yjt
Endonuclease-mediated Allele Detail
Summary
Symbol: Fam171a2em1Yjt
Name: family with sequence similarity 171, member A2; endonuclease-mediated mutation 1, Jin-Tai Yu
MGI ID: MGI:8187547
Gene: Fam171a2  Location: Chr11:102327807-102338508 bp, - strand  Genetic Position: Chr11, 66.29 cM
Alliance: Fam171a2em1Yjt page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    CRISPR/cas9 mediated recombination deleted exons 4-7. (J:362731)
Inheritance:    Not Specified
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fam171a2 Mutation:  31 strains or lines available
References
Original:  J:362731 Wu KM, et al., Neuronal FAM171A2 mediates alpha-synuclein fibril uptake and drives Parkinson's disease. Science. 2025 Feb 21;387(6736):892-900
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory