Phenotypes associated with this allele

• Allele Symbol: Barx1^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:7785507
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Barx1^em1(IMPC)Ccpcz/Barx1^em1(IMPC)Ccpcz	C57BL/6NCrl-Barx1^em1(IMPC)Ccpcz/Ccpcz	MGI:8298222
ht2	Barx1^em1(IMPC)Ccpcz/Barx1^+	C57BL/6NCrl-Barx1^em1(IMPC)Ccpcz/Ccpcz	MGI:8298221

Genotype
MGI:8298222

hm1

• Allelic Composition: Barx1^{em1(IMPC)Ccpcz}/Barx1^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Barx1^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Barx1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal blood vessel morphology ( J:211773 )

IMPC - CCP-IMG

craniofacial

abnormal facial morphology ( J:211773 )

IMPC - CCP-IMG

cleft palate ( J:211773 )

IMPC - CCP-IMG

abnormal head shape ( J:211773 )

IMPC - CCP-IMG

digestive/alimentary system

cleft palate ( J:211773 )

IMPC - CCP-IMG

embryo

abnormal embryo development ( J:211773 )

IMPC - CCP-IMG

embryonic growth retardation ( J:211773 )

IMPC - CCP-IMG

abnormal embryo size ( J:211773 )

IMPC - CCP-IMG

growth/size/body

abnormal facial morphology ( J:211773 )

IMPC - CCP-IMG

cleft palate ( J:211773 )

IMPC - CCP-IMG

abnormal head shape ( J:211773 )

IMPC - CCP-IMG

embryonic growth retardation ( J:211773 )

IMPC - CCP-IMG

abnormal embryo size ( J:211773 )

IMPC - CCP-IMG

abnormal head size ( J:211773 )

IMPC - CCP-IMG

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - CCP-IMG

Genotype
MGI:8298221

ht2

• Allelic Composition: Barx1^{em1(IMPC)Ccpcz}/Barx1⁺
• Genetic Background: C57BL/6NCrl-Barx1^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Barx1

behavior/neurological

decreased exploration in new environment ( J:211773 )

♂

IMPC - CCP-IMG

decreased locomotor activity ( J:211773 )

♂

IMPC - CCP-IMG

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

prolonged PR interval ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

hematopoietic system

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

homeostasis/metabolism

increased circulating alanine transaminase level ( J:211773 )

IMPC - CCP-IMG

increased circulating lactate dehydrogenase level ( J:211773 )

♀

IMPC - CCP-IMG

immune system

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

liver/biliary system

abnormal liver morphology ( J:211773 )

♀

IMPC - CCP-IMG

small liver ( J:211773 )

♀

IMPC - CCP-IMG

respiratory system

increased airway resistance ( J:211773 )

♂

IMPC - CCP-IMG