Phenotypes associated with this allele

• Allele Symbol: Qrich1^em2Nki
• Allele Name: endonuclease-mediated mutation 2, The Netherlands Cancer Institute
• Allele ID: MGI:7785050
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Qrich1^em2Nki/Qrich1^em2Nki	involves: C57BL/6JRj	MGI:8259583

Genotype
MGI:8259583

hm1

• Allelic Composition: Qrich1^em2Nki/Qrich1^em2Nki
• Genetic Background: involves: C57BL/6JRj

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, incomplete penetrance ( J:369749 )

• at E9.5 to E14.5, embryos are seen at declining frequency during gestation

prenatal lethality, complete penetrance ( J:369749 )

• no live mice are obtained

cellular

increased embryonic neuroepithelium apoptosis ( J:369749 )

• embryos display and increase in the number of apoptotic cells in the neuroepithelia of different brain regions

embryo

thin placenta labyrinth ( J:369749 )

hematopoietic system

decreased mean corpuscular hemoglobin ( J:369749 )

• embryos display hypochromasia

nervous system

increased embryonic neuroepithelium apoptosis ( J:369749 )

• embryos display and increase in the number of apoptotic cells in the neuroepithelia of different brain regions