Qrich1^em2Nki
Endonuclease-mediated Allele Detail

Summary

• Symbol: Qrich1^em2Nki
• Name: glutamine-rich 1; endonuclease-mediated mutation 2, The Netherlands Cancer Institute
• MGI ID: MGI:7785050
• Synonyms: QRICH1^KO
• Gene: Qrich1 Location: Chr9:108394010-108437366 bp, + strand Genetic Position: Chr9, 59.45 cM
• Alliance: Qrich1^em2Nki page

Mutation origin

• Strain of Origin: C57BL/6JRj

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A knockout allele was achieved by two frameshift deletions, a 5bp (CTCAT) deletion at CRISPR/Cas9 target sequence: 5'-GATGTACTCTTCAAATGAGA TGG-3' and a 14 bp deletion (GGGTGGGAACTGCA) at CRISPR/Cas9 target sequence: 5'-CCATGGTGTACCAGCAGGGT GGG-3' (J:369749)

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Qrich1 Mutation: 60 strains or lines available

References

• Original: J:369749 Bianchi D, et al., Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression. Science. 2025 Jul 3;389(6755):eadv2861
• All: 1 reference(s)