Phenotypes associated with this allele

• Allele Symbol: Col2a1^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:7715163
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Col2a1^em1(IMPC)Ccpcz/Col2a1^em1(IMPC)Ccpcz	C57BL/6NCrl-Col2a1^em1(IMPC)Ccpcz/Ccpcz	MGI:8176155
ht2	Col2a1^em1(IMPC)Ccpcz/Col2a1^+	C57BL/6NCrl-Col2a1^em1(IMPC)Ccpcz/Ccpcz	MGI:8176154

Genotype
MGI:8176155

hm1

• Allelic Composition: Col2a1^{em1(IMPC)Ccpcz}/Col2a1^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Col2a1^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Col2a1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - CCP-IMG

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - CCP-IMG

craniofacial

abnormal facial morphology ( J:211773 )

IMPC - CCP-IMG

cleft palate ( J:211773 )

IMPC - CCP-IMG

protruding tongue ( J:211773 )

IMPC - CCP-IMG

abnormal head shape ( J:211773 )

IMPC - CCP-IMG

digestive/alimentary system

cleft palate ( J:211773 )

IMPC - CCP-IMG

protruding tongue ( J:211773 )

IMPC - CCP-IMG

embryo

abnormal embryo development ( J:211773 )

IMPC - CCP-IMG

abnormal embryo size ( J:211773 )

IMPC - CCP-IMG

growth/size/body

abnormal facial morphology ( J:211773 )

IMPC - CCP-IMG

cleft palate ( J:211773 )

IMPC - CCP-IMG

protruding tongue ( J:211773 )

IMPC - CCP-IMG

abnormal head shape ( J:211773 )

IMPC - CCP-IMG

abnormal embryo size ( J:211773 )

IMPC - CCP-IMG

abnormal body wall morphology ( J:211773 )

IMPC - CCP-IMG

abnormal head size ( J:211773 )

IMPC - CCP-IMG

homeostasis/metabolism

edema ( J:211773 )

IMPC - CCP-IMG

limbs/digits/tail

abnormal limb morphology ( J:211773 )

IMPC - CCP-IMG

abnormal tail morphology ( J:211773 )

IMPC - CCP-IMG

liver/biliary system

abnormal liver size ( J:211773 )

IMPC - CCP-IMG

respiratory system

respiratory system phenotype ( J:211773 )

IMPC - CCP-IMG

Genotype
MGI:8176154

ht2

• Allelic Composition: Col2a1^{em1(IMPC)Ccpcz}/Col2a1⁺
• Genetic Background: C57BL/6NCrl-Col2a1^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Col2a1

craniofacial

abnormal cranium morphology ( J:211773 )

♂

IMPC - CCP-IMG

abnormal maxilla morphology ( J:211773 )

IMPC - CCP-IMG

abnormal zygomatic bone morphology ( J:211773 )

IMPC - CCP-IMG

hematopoietic system

increased monocyte cell number ( J:211773 )

♂

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♂

IMPC - CCP-IMG

immune system

increased monocyte cell number ( J:211773 )

♂

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♂

IMPC - CCP-IMG

integument

abnormal skin morphology ( J:211773 )

♀

IMPC - CCP-IMG

skeleton

abnormal cranium morphology ( J:211773 )

♂

IMPC - CCP-IMG

abnormal maxilla morphology ( J:211773 )

IMPC - CCP-IMG

abnormal zygomatic bone morphology ( J:211773 )

IMPC - CCP-IMG

kyphosis ( J:211773 )

♀

IMPC - CCP-IMG