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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Il31tm1.1Ysfk
targeted mutation 1.1, Yoshinori Fukui
MGI:7643916
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Dock8tm1Ysfk/Dock8tm1Ysfk
Il31tm1.1Ysfk/Il31tm1.1Ysfk
Tg(TcrAND)53Hed/0 		involves: C57BL/6 * SJL MGI:7643974


Genotype
MGI:7643974
cx1
Allelic
Composition		 Dock8tm1Ysfk/Dock8tm1Ysfk
Il31tm1.1Ysfk/Il31tm1.1Ysfk
Tg(TcrAND)53Hed/0
Genetic
Background		 involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock8tm1Ysfk mutation (0 available); any Dock8 mutation (101 available)
Il31tm1.1Ysfk mutation (0 available); any Il31 mutation (14 available)
Tg(TcrAND)53Hed mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
integument phenotype ( J:305132 )
N
• mice show improved skin inflammation and scratching behavior and do not develop atopic dermatitis-like skin disease that is seen in Dock8tm1Ysfk/Dock8tm1Ysfk Tg(TcrAND)53Hed/0 mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory