Phenotypes associated with this allele

• Allele Symbol: Gt(ROSA)26Sor^{em1(Ube2s)Chaw}
• Allele Name: endonuclease-mediated mutation 1, Changjiang Weng
• Allele ID: MGI:7621224
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ot1	Gt(ROSA)26Sor^em1(Ube2s)Chaw/?	involves: C57BL/6	MGI:7621244

Genotype
MGI:7621244

ot1

• Allelic Composition: Gt(ROSA)26Sor^{em1(Ube2s)Chaw}/?
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

increased susceptibility to Picornaviridae infection induced morbidity/mortality ( J:306461 )

• decreased survival and increased virus levels after infection with

homeostasis/metabolism

decreased interferon level ( J:306461 )

• levels of Ifnb1 in the heart and brain are lower at 48 and 72 h after encephalomyocarditis virus (EMCV) infection

immune system

decreased interferon level ( J:306461 )

• levels of Ifnb1 in the heart and brain are lower at 48 and 72 h after encephalomyocarditis virus (EMCV) infection

increased susceptibility to Picornaviridae infection induced morbidity/mortality ( J:306461 )

• decreased survival and increased virus levels after infection with