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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ces1ce
variant e
MGI:7595768
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
a/a
Ces1ce/Ces1ce
B6;D2-a Ces1ce/EiJ MGI:7596325


Genotype
MGI:7596325
cx1
Allelic
Composition
a/a
Ces1ce/Ces1ce
Genetic
Background
B6;D2-a Ces1ce/EiJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (229 available); any a mutation (463 available)
Ces1ce mutation (2 available); any Ces1c mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• 3-fold decreased in total plasma esterases activity compared with B6D2F1
• 200-fold reduction in SN-38 production after incubation with CPT-11 in vitro





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory