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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Polr1aem3Knwea
endonuclease-mediated mutation 3, Kathryn Nicole Weaver
MGI:7526145
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Polr1aem3Knwea/Polr1aem3Knwea C57BL/6-Polr1aem3Knwea MGI:7526446
ht2
 		Polr1aem3Knwea/Polr1a+ C57BL/6-Polr1aem3Knwea MGI:7526442
ht3
 		Polr1aem3Knwea/Polr1atm1a(EUCOMM)Hmgu involves: C57BL/6 * C57BL/6N MGI:7526449
ht4
 		Polr1aem3Knwea/Polr1atm1d(EUCOMM)Hmgu involves: C57BL/6 * C57BL/6N MGI:7526451


Genotype
MGI:7526446
hm1
Allelic
Composition		 Polr1aem3Knwea/Polr1aem3Knwea
Genetic
Background		 C57BL/6-Polr1aem3Knwea
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Polr1aem3Knwea mutation (0 available); any Polr1a mutation (93 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:335489 )
• mice born at expected Mendelian ratios and sex ratios

growth/size/body
growth/size/body region phenotype ( J:335489 )
• no obvious phenotype




Genotype
MGI:7526442
ht2
Allelic
Composition		 Polr1aem3Knwea/Polr1a+
Genetic
Background		 C57BL/6-Polr1aem3Knwea
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Polr1aem3Knwea mutation (0 available); any Polr1a mutation (93 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:335489 )
• mice born at expected Mendelian ratios and normal sex ratio

growth/size/body
growth/size/body region phenotype ( J:335489 )
• no obvious phenotype




Genotype
MGI:7526449
ht3
Allelic
Composition		 Polr1aem3Knwea/Polr1atm1a(EUCOMM)Hmgu
Genetic
Background		 involves: C57BL/6 * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Polr1aem3Knwea mutation (0 available); any Polr1a mutation (93 available)
Polr1atm1a(EUCOMM)Hmgu mutation (1 available); any Polr1a mutation (93 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:335489 )
• mice born at expected Mendelian ratios and sex ratios

growth/size/body
growth/size/body region phenotype ( J:335489 )
• no obvious phenotype




Genotype
MGI:7526451
ht4
Allelic
Composition		 Polr1aem3Knwea/Polr1atm1d(EUCOMM)Hmgu
Genetic
Background		 involves: C57BL/6 * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Polr1aem3Knwea mutation (0 available); any Polr1a mutation (93 available)
Polr1atm1d(EUCOMM)Hmgu mutation (0 available); any Polr1a mutation (93 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:335489 )
• mice born at expected Mendelian ratios and sex ratios

growth/size/body
growth/size/body region phenotype ( J:335489 )
• no obvious phenotype




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory