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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nesem1Pqt
endonuclease-mediated mutation 1, Paul Q Thomas
MGI:7447464
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nesem1Pqt/Nesem1Pqt C57BL/6J-Nesem1Pqt MGI:7447493
ht2
 		Nesem1Pqt/Nesem2Pqt C57BL/6J-Nesem1Pqt/Nesem2Pqt MGI:7447495
cx3
 		Nesem1Pqt/Nes+
Rr400em1Pqt/Rr400+ 		C57BL/6J-Nesem1Pqt Rr400em1Pqt MGI:7447497


Genotype
MGI:7447493
hm1
Allelic
Composition		 Nesem1Pqt/Nesem1Pqt
Genetic
Background		 C57BL/6J-Nesem1Pqt
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nesem1Pqt mutation (0 available); any Nes mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:314040 )
• viable, mice born at expected Mendelian ratios

growth/size/body
growth/size/body region phenotype ( J:314040 )
• no obvious phenotype

nervous system
nervous system phenotype ( J:314040 )
• no obvious CNS phenotype




Genotype
MGI:7447495
ht2
Allelic
Composition		 Nesem1Pqt/Nesem2Pqt
Genetic
Background		 C57BL/6J-Nesem1Pqt/Nesem2Pqt
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nesem1Pqt mutation (0 available); any Nes mutation (84 available)
Nesem2Pqt mutation (0 available); any Nes mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:314040 )
• viable, mice born at expected Mendelian ratios

growth/size/body
growth/size/body region phenotype ( J:314040 )
• no obvious phenotype

nervous system
nervous system phenotype ( J:314040 )
• no obvious CNS phenotype




Genotype
MGI:7447497
cx3
Allelic
Composition		 Nesem1Pqt/Nes+
Rr400em1Pqt/Rr400+
Genetic
Background		 C57BL/6J-Nesem1Pqt Rr400em1Pqt
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nesem1Pqt mutation (0 available); any Nes mutation (84 available)
Rr400em1Pqt mutation (0 available); any Rr400 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:314040 )
• viable, mice born at expected Mendelian ratios

growth/size/body
growth/size/body region phenotype ( J:314040 )
• no obvious phenotype

nervous system
nervous system phenotype ( J:314040 )
• no obvious CNS phenotype




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory