Phenotypes associated with this allele

• Allele Symbol: Rr394^em1Bhao
• Allele Name: endonuclease-mediated mutation 1, Bingtao Hao
• Allele ID: MGI:7444371
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rr394^em1Bhao/Rr394^em1Bhao	Not Specified	MGI:7444376

Genotype
MGI:7444376

hm1

• Allelic Composition: Rr394^em1Bhao/Rr394^em1Bhao
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased thymocyte number ( J:333961 )

• ~35% reduction

increased DN3 thymocyte number ( J:333961 )

abnormal T cell receptor alpha chain V-J recombination ( J:333961 )

• increased use of 5 and reduced use of 3 J segments

• increased use of proximal and reduced use of central and distal V segments

hematopoietic system

hematopoietic system phenotype ( J:333961 )

N • normal DN, DP and SP T cell proportions in thymus

N • normal lifespan in vitro

decreased thymocyte number ( J:333961 )

• ~35% reduction

increased DN3 thymocyte number ( J:333961 )

abnormal T cell receptor alpha chain V-J recombination ( J:333961 )

• increased use of 5 and reduced use of 3 J segments

• increased use of proximal and reduced use of central and distal V segments

endocrine/exocrine glands

decreased thymocyte number ( J:333961 )

• ~35% reduction

increased DN3 thymocyte number ( J:333961 )