Phenotypes associated with this allele

• Allele Symbol: Rr348^tm1.1Drhi
• Allele Name: targeted mutation 1.1, Douglas R Higgs
• Allele ID: MGI:7433175
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Rr348^tm1.1Drhi/Rr348^tm1.1Drhi Rr349^tm1.1Wgw/Rr349^tm1.1Wgw	involves: 129P2/OlaHsd	MGI:7433188
cx2	Rr348^tm1.1Drhi/Rr348^+ Rr349^tm1.1Wgw/Rr349^+	Not Specified	MGI:7433190

Genotype
MGI:7433188

cx1

• Allelic Composition: Rr348^tm1.1Drhi/Rr348^tm1.1Drhi; Rr349^tm1.1Wgw/Rr349^tm1.1Wgw
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

hemorrhage ( J:259286 )

• in E14.5 embryos

embryo

decreased embryo size ( J:259286 )

• E14.5 embryos

growth/size/body

decreased embryo size ( J:259286 )

• E14.5 embryos

nuchal edema ( J:259286 )

• in E14.5 embryos

homeostasis/metabolism

nuchal edema ( J:259286 )

• in E14.5 embryos

integument

nuchal edema ( J:259286 )

• in E14.5 embryos

pallor ( J:259286 )

• in E14.5 embryos

mortality/aging

prenatal lethality, complete penetrance ( J:259286 )

• no homozygous mice born

Genotype
MGI:7433190

cx2

• Allelic Composition: Rr348^tm1.1Drhi/Rr348⁺; Rr349^tm1.1Wgw/Rr349⁺
• Genetic Background: Not Specified

hematopoietic system

decreased mean corpuscular hemoglobin ( J:259286 )

decreased mean corpuscular volume ( J:259286 )

reticulocytosis ( J:259286 )