Phenotypes associated with this allele

• Allele Symbol: Lrba^em1Suc
• Allele Name: endonuclease-mediated mutation 1, Shinichi Uchida
• Allele ID: MGI:7431112
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lrba^em1Suc/Lrba^em1Suc	C57BL/6J-Lrba^em1Suc	MGI:8353918

Genotype
MGI:8353918

hm1

• Allelic Composition: Lrba^em1Suc/Lrba^em1Suc
• Genetic Background: C57BL/6J-Lrba^em1Suc

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating bicarbonate level ( J:384972 )

• when on low- or medium-sodium diet

decreased circulating sodium level ( J:384972 )

• when on low- or medium-sodium diet

decreased circulating chloride level ( J:384972 )

• when on low- or medium-sodium diet

increased urine sodium level ( J:384972 )

• when on low-sodium diet

• when on medium-sodium diet

renal/urinary system

increased urine sodium level ( J:384972 )

• when on low-sodium diet

• when on medium-sodium diet

isosthenuria ( J:384972 )

• reduced urine osmolality after desmopressin administration

• greater body weight loss after water deprivation