Phenotypes associated with this allele

• Allele Symbol: Fgf23^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:7425686
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fgf23^em1(IMPC)Ccpcz/Fgf23^em1(IMPC)Ccpcz	C57BL/6NCrl-Fgf23^em1(IMPC)Ccpcz/Ccpcz	MGI:7768332
ht2	Fgf23^em1(IMPC)Ccpcz/Fgf23^+	C57BL/6NCrl-Fgf23^em1(IMPC)Ccpcz/Ccpcz	MGI:8176192

Genotype
MGI:7768332

hm1

• Allelic Composition: Fgf23^{em1(IMPC)Ccpcz}/Fgf23^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Fgf23^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Fgf23

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

♀

IMPC - CCP-IMG

abnormal anxiety-related response ( J:211773 )

♀

IMPC - CCP-IMG

increased anxiety-related response ( J:211773 )

♀

IMPC - CCP-IMG

increased freezing behavior ( J:211773 )

♀

IMPC - CCP-IMG

abnormal startle reflex ( J:211773 )

♀

IMPC - CCP-IMG

decreased startle reflex ( J:211773 )

♀

IMPC - CCP-IMG

decreased locomotor activity ( J:211773 )

♀

IMPC - CCP-IMG

Genotype
MGI:8176192

ht2

• Allelic Composition: Fgf23^{em1(IMPC)Ccpcz}/Fgf23⁺
• Genetic Background: C57BL/6NCrl-Fgf23^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Fgf23

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - CCP-IMG

hematopoietic system

abnormal spleen morphology ( J:211773 )

♂

IMPC - CCP-IMG

homeostasis/metabolism

increased blood urea nitrogen level ( J:211773 )

♀

IMPC - CCP-IMG

decreased circulating iron level ( J:211773 )

♀

IMPC - CCP-IMG

decreased circulating chloride level ( J:211773 )

♀

IMPC - CCP-IMG

immune system

abnormal spleen morphology ( J:211773 )

♂

IMPC - CCP-IMG

respiratory system

increased lung elastance ( J:211773 )

IMPC - CCP-IMG

vision/eye

abnormal retina vasculature morphology ( J:211773 )

IMPC - CCP-IMG