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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Del(15Rr316124-Rr313939)2Fsp
deletion, Chr 15, Francois Spitz 2
MGI:7411151
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Del(15Rr316124-Rr313939)2Fsp/Del(15Rr316124-Rr313939)2Fsp Not Specified MGI:7411327
cx2
 		Del(15Rr316124-Rr313939)2Fsp/+
Myctm1Atp/Myc+ 		involves: 129P2/OlaHsd * C57BL/6 MGI:7411328
cx3
 		Del(15Rr316124-Rr313939)2Fsp/+
Rr307328em1Fsp/Rr307328+ 		involves: C57BL/6 MGI:7411330
cx4
 		Del(15Rr316124-Rr313939)2Fsp/+
Rr331em1Fsp/Rr331+ 		involves: C57BL/6 MGI:7411333


Genotype
MGI:7411327
hm1
Allelic
Composition		 Del(15Rr316124-Rr313939)2Fsp/Del(15Rr316124-Rr313939)2Fsp
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:257739 )
N
• normal number of MMP1, HSC and T cells and erythrocytes in bone marrow
increased myeloid cell number in bone marrow ( J:257739 )
• increased multipotent progenitor (MMP) populations 2, 3 and 4
• normal number of MMP1 and HSC cells
decreased bone marrow cell number ( J:257739 )
• decreased B cell and granulocyte numbers
• normal number of MMP1 and HSC cells
increased megakaryocyte cell number ( J:257739 )
• increased megakaryocytic cell number in bone marrow
decreased granulocyte number ( J:257739 )
• in bone marrow
decreased B cell number ( J:257739 )
• in bone marrow

immune system
decreased granulocyte number ( J:257739 )
• in bone marrow
decreased B cell number ( J:257739 )
• in bone marrow

mortality/aging
mortality/aging ( J:257739 )
N
• viable

growth/size/body
growth/size/body region phenotype ( J:257739 )
N
• normal weight




Genotype
MGI:7411328
cx2
Allelic
Composition		 Del(15Rr316124-Rr313939)2Fsp/+
Myctm1Atp/Myc+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(15Rr316124-Rr313939)2Fsp mutation (0 available); any Del(15Rr316124-Rr313939)2Fsp mutation (0 available)
Myctm1Atp mutation (0 available); any Myc mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:257739 )
N
• normal number of MMP1, HSC and T cells and erythrocytes in bone marrow
increased myeloid cell number in bone marrow ( J:257739 )
• increased multipotent progenitor (MMP) populations 3 and 4
• normal number of MMP1 and HSC cells
decreased bone marrow cell number ( J:257739 )
• decreased B cell and granulocyte numbers
• normal number of MMP1 and HSC cells
increased megakaryocyte cell number ( J:257739 )
• increased megakaryocytic cell number in bone marrow
decreased granulocyte number ( J:257739 )
• in bone marrow
decreased B cell number ( J:257739 )
• in bone marrow

immune system
decreased granulocyte number ( J:257739 )
• in bone marrow
decreased B cell number ( J:257739 )
• in bone marrow




Genotype
MGI:7411330
cx3
Allelic
Composition		 Del(15Rr316124-Rr313939)2Fsp/+
Rr307328em1Fsp/Rr307328+
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased B cell number ( J:257739 )
• reduced total B220+ B cell number
increased pre-B cell number ( J:257739 )
• accumulation of B220+ CD24- CD43+ PreProB cells

immune system
decreased B cell number ( J:257739 )
• reduced total B220+ B cell number
increased pre-B cell number ( J:257739 )
• accumulation of B220+ CD24- CD43+ PreProB cells




Genotype
MGI:7411333
cx4
Allelic
Composition		 Del(15Rr316124-Rr313939)2Fsp/+
Rr331em1Fsp/Rr331+
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased B cell number ( J:257739 )
• reduced total B220+ B cell number
increased pre-B cell number ( J:257739 )
• accumulation of B220+ CD24- CD43+ PreProB cells

immune system
decreased B cell number ( J:257739 )
• reduced total B220+ B cell number
increased pre-B cell number ( J:257739 )
• accumulation of B220+ CD24- CD43+ PreProB cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory