Phenotypes associated with this allele

• Allele Symbol: Zmym3^em1Hncs
• Allele Name: endonuclease-mediated mutation 1, Chunsheng Han
• Allele ID: MGI:7287466
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Zmym3^em1Hncs/Zmym3^em1Hncs	involves: C57BL/6J * CBA	MGI:7287521

Genotype
MGI:7287521

hm1

• Allelic Composition: Zmym3^em1Hncs/Zmym3^em1Hncs
• Genetic Background: involves: C57BL/6J * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

oligozoospermia ( J:324172 )

• beginning 2 months from birth

abnormal spermatid morphology ( J:324172 )

• reduced number of round spermatids and elongated spermatids

arrest of male meiosis ( J:324172 )

• accumulation of MI spermatocytes

increased male germ cell apoptosis ( J:324172 )

small testis ( J:324172 )

• beginning 2 months from birth

decreased epididymis weight ( J:324172 )

male infertility ( J:324172 )

• at 6 months of age

reduced male fertility ( J:324172 )

• beginning 2 months from birth

endocrine/exocrine glands

small testis ( J:324172 )

• beginning 2 months from birth

cellular

oligozoospermia ( J:324172 )

• beginning 2 months from birth

abnormal spermatid morphology ( J:324172 )

• reduced number of round spermatids and elongated spermatids

arrest of male meiosis ( J:324172 )

• accumulation of MI spermatocytes

increased male germ cell apoptosis ( J:324172 )