All Phenotypes Uba1<em1Imat> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Uba1^em1Imat
endonuclease-mediated mutation 1, Isao Matsuo
MGI:7287390

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Uba1^em1Imat/Uba1⁺ Usp39^em1Imat/Usp39^em1Imat	CD1-Usp39^em1Imat Uba1^em1Imat	MGI:7287418
ot2	Uba1^em1Imat/Y	CD1-Uba1^em1Imat	MGI:7287416

Allelic Composition	Uba1^em1Imat/Uba1⁺ Usp39^em1Imat/Usp39^em1Imat
Genetic Background	CD1-Usp39^em1Imat Uba1^em1Imat

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Uba1^em1Imat mutation (0 available); any Uba1 mutation (3 available)
Usp39^em1Imat mutation (0 available); any Usp39 mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal primitive streak formation ( J:324183 )

• partial at E6.5 with mesoderm cells migrating toward the anterior side unlike in Usp39^em1Imat homozygotes

Allelic Composition	Uba1^em1Imat/Y
Genetic Background	CD1-Uba1^em1Imat

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Uba1^em1Imat mutation (0 available); any Uba1 mutation (3 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality at implantation, complete penetrance ( J:324183 )

• mice exhibit peri-implantation lethality

embryo

abnormal embryo morphology ( J:324183 )

• at the blastocyst stage

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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