Phenotypes associated with this allele

• Allele Symbol: Gzf1^em1(IMPC)Tcp
• Allele Name: endonuclease-mediated mutation 1, The Centre for Phenogenomics
• Allele ID: MGI:7256894
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gzf1^em1(IMPC)Tcp/Gzf1^em1(IMPC)Tcp	C57BL/6NCrl-Gzf1^em1(IMPC)Tcp/Tcp	MGI:7414911
ht2	Gzf1^em1(IMPC)Tcp/Gzf1^+	C57BL/6NCrl-Gzf1^em1(IMPC)Tcp/Tcp	MGI:7414910

Genotype
MGI:7414911

hm1

• Allelic Composition: Gzf1^em1(IMPC)Tcp/Gzf1^em1(IMPC)Tcp
• Genetic Background: C57BL/6NCrl-Gzf1^em1(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Gzf1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

♀

IMPC - TCP

cardiovascular system

abnormal heartbeat ( J:211773 )

IMPC - TCP

growth/size/body

decreased lean body mass ( J:211773 )

♀

IMPC - TCP

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - TCP

homeostasis/metabolism

decreased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - TCP

decreased circulating total protein level ( J:211773 )

♀

IMPC - TCP

integument

abnormal skin morphology ( J:211773 )

♂

IMPC - TCP

limbs/digits/tail

short tibia ( J:211773 )

♀

IMPC - TCP

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - TCP

skeleton

short tibia ( J:211773 )

♀

IMPC - TCP

abnormal bone structure ( J:211773 )

♀

IMPC - TCP

vision/eye

abnormal eye morphology ( J:211773 )

♀

IMPC - TCP

Genotype
MGI:7414910

ht2

• Allelic Composition: Gzf1^em1(IMPC)Tcp/Gzf1⁺
• Genetic Background: C57BL/6NCrl-Gzf1^em1(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Gzf1

hematopoietic system

decreased mean corpuscular volume ( J:211773 )

IMPC - TCP

homeostasis/metabolism

decreased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - TCP

vision/eye

abnormal lens morphology ( J:211773 )

♂

IMPC - TCP

cataract ( J:211773 )

♂

IMPC - TCP