Phenotypes associated with this allele

• Allele Symbol: Usp38^em1Cya
• Allele Name: endonuclease-mediated mutation 1, Cyagen Biosciences
• Allele ID: MGI:7256446
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Usp38^em1Cya/Usp38^em1Cya	C57BL/6-Usp38^em1Cya	MGI:7256451

Genotype
MGI:7256451

hm1

• Allelic Composition: Usp38^em1Cya/Usp38^em1Cya
• Genetic Background: C57BL/6-Usp38^em1Cya

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

increased susceptibility to xenobiotic induced morbidity/mortality ( J:321973 )

• induced by bleomycin

respiratory system

lung inflammation ( J:321973 )

• induced by bleomycin

pulmonary fibrosis ( J:321973 )

• induced by bleomycin

homeostasis/metabolism

increased susceptibility to xenobiotic induced morbidity/mortality ( J:321973 )

• induced by bleomycin

increased physiological sensitivity to xenobiotic ( J:321973 )

• mice exposed to bleomycin exhibit increased inflammatory damage, fibrosis, and mortality compared with wild-type mice

immune system

lung inflammation ( J:321973 )

• induced by bleomycin