Phenotypes associated with this allele

• Allele Symbol: Nek9^em1Nmz
• Allele Name: endonuclease-mediated mutation 1, Noboru Mizushima
• Allele ID: MGI:6887930
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nek9^em1Nmz/Nek9^em1Nmz	C57BL/6-Nek9^em1Nmz	MGI:6887944

Genotype
MGI:6887944

hm1

• Allelic Composition: Nek9^em1Nmz/Nek9^em1Nmz
• Genetic Background: C57BL/6-Nek9^em1Nmz

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

abnormal renal tubule epithelial cell primary cilium morphology ( J:314513 )

• fewer ciliated proximal tubular cells in the cortical region

• shorter cilia on proximal tubular cells in the cortical region

impaired autophagy ( J:314513 )

• failure to co-locate with MYH9 at autophagic membranes

renal/urinary system

renal/urinary system phenotype ( J:314513 )

N

abnormal renal tubule epithelial cell primary cilium morphology ( J:314513 )

• fewer ciliated proximal tubular cells in the cortical region

• shorter cilia on proximal tubular cells in the cortical region

renal tubule hypertrophy ( J:314513 )

homeostasis/metabolism

impaired autophagy ( J:314513 )

• failure to co-locate with MYH9 at autophagic membranes

mortality/aging

mortality/aging ( J:314513 )

N • viable

growth/size/body

growth/size/body region phenotype ( J:314513 )

N • normal size and weight

reproductive system

reproductive system phenotype ( J:314513 )

N • fertile