Phenotypes associated with this allele

• Allele Symbol: Rpl10l^em1Qsh
• Allele Name: endonuclease-mediated mutation 1, Qinghua Shi
• Allele ID: MGI:6865773
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rpl10l^em1Qsh/Rpl10l^em1Qsh	involves: C57BL/6 * DBA/2J	MGI:6865784

Genotype
MGI:6865784

hm1

• Allelic Composition: Rpl10l^em1Qsh/Rpl10l^em1Qsh
• Genetic Background: involves: C57BL/6 * DBA/2J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

azoospermia ( J:319673 )

• however, expression of a transgene containing the wild-type endogenous gene restores fspermatogenesis

arrest of male meiosis ( J:319673 )

• at the transition from prophase to metaphase in meiosis I with disruption in ribosome biogenesis in late-prophase spermatocytes

increased male germ cell apoptosis ( J:319673 )

testis hypoplasia ( J:319673 )

male infertility ( J:319673 )

• however, expression of a transgene containing the wild-type endogenous gene restores fertility

cellular

azoospermia ( J:319673 )

• however, expression of a transgene containing the wild-type endogenous gene restores fspermatogenesis

arrest of male meiosis ( J:319673 )

• at the transition from prophase to metaphase in meiosis I with disruption in ribosome biogenesis in late-prophase spermatocytes

increased male germ cell apoptosis ( J:319673 )

endocrine/exocrine glands

testis hypoplasia ( J:319673 )