All Phenotypes Selenow<tm1c(EUCOMM)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Selenow^{tm1c(EUCOMM)Wtsi}
targeted mutation 1c, Wellcome Trust Sanger Institute
MGI:6845150

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Lyz2^tm1(cre)Ifo/Lyz2⁺ Selenow^{tm1c(EUCOMM)Wtsi}/Selenow^{tm1c(EUCOMM)Wtsi}	B6.Cg-Selenow^{tm1c(EUCOMM)Wtsi} Lyz2^tm1(cre)Ifo	MGI:6850175

Allelic Composition	Lyz2^tm1(cre)Ifo/Lyz2⁺ Selenow^{tm1c(EUCOMM)Wtsi}/Selenow^{tm1c(EUCOMM)Wtsi}
Genetic Background	B6.Cg-Selenow^{tm1c(EUCOMM)Wtsi} Lyz2^tm1(cre)Ifo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lyz2^tm1(cre)Ifo mutation (16 available); any Lyz2 mutation (40 available)
Selenow^{tm1c(EUCOMM)Wtsi} mutation (0 available); any Selenow mutation (17 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal osteoclast differentiation ( J:317012 )

• reduction in osteoclast formation

increased bone mass ( J:317012 )

decreased bone ossification ( J:317012 )

• mice exhibit a decrease in bone formation rate

hematopoietic system

abnormal osteoclast differentiation ( J:317012 )

• reduction in osteoclast formation

immune system

abnormal osteoclast differentiation ( J:317012 )

• reduction in osteoclast formation

cellular

abnormal osteoclast differentiation ( J:317012 )

• reduction in osteoclast formation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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