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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Ins2-Mirc13)E4Biat
transgene insertion E4, Biomodels Austria
MGI:6828985
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Trp53tm1Tyj/Trp53+
Tg(Ins2-Mirc13)E4Biat/0
involves: 129S2/SvPas * C57BL/6N MGI:6829612
cx2
Badtm1Sjk/Badtm1Sjk
Tg(Ins2-Mirc13)E4Biat/0
involves: 129X1/SvJ * C57BL/6N MGI:6829608
cx3
Baxtm1Sjk/Baxtm1Sjk
Tg(Ins2-Mirc13)E4Biat/0
involves: 129X1/SvJ * C57BL/6N MGI:6829609
cx4
Tg(Ins2-Mirc13)E4Biat/0
Tg(RIP1-Tag)2Dh/0
involves: C57BL/6J * C57BL/6N * DBA/2J MGI:6829611
tg5
Tg(Ins2-Mirc13)E4Biat/0 C57BL/6N-Tg(Ins2-Mirc13)E4Biat MGI:6829614


Genotype
MGI:6829612
cx1
Allelic
Composition
Trp53tm1Tyj/Trp53+
Tg(Ins2-Mirc13)E4Biat/0
Genetic
Background
involves: 129S2/SvPas * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Ins2-Mirc13)E4Biat mutation (0 available)
Trp53tm1Tyj mutation (12 available); any Trp53 mutation (232 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
N
• mice exhibit normal glucose serum levels unlike mice expressing the transgene alone




Genotype
MGI:6829608
cx2
Allelic
Composition
Badtm1Sjk/Badtm1Sjk
Tg(Ins2-Mirc13)E4Biat/0
Genetic
Background
involves: 129X1/SvJ * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Badtm1Sjk mutation (0 available); any Bad mutation (25 available)
Tg(Ins2-Mirc13)E4Biat mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• after a 4 h fast, mice exhibit increased blood glucose levels as in mice with the transgene alone




Genotype
MGI:6829609
cx3
Allelic
Composition
Baxtm1Sjk/Baxtm1Sjk
Tg(Ins2-Mirc13)E4Biat/0
Genetic
Background
involves: 129X1/SvJ * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Baxtm1Sjk mutation (1 available); any Bax mutation (24 available)
Tg(Ins2-Mirc13)E4Biat mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
N
• mice exhibit normal beta cell mass unlike mice expressing the transgene alone

homeostasis/metabolism
N
• mice exhibit normal glucose serum levels after a 4 h fast unlike mice expressing the transgene alone




Genotype
MGI:6829611
cx4
Allelic
Composition
Tg(Ins2-Mirc13)E4Biat/0
Tg(RIP1-Tag)2Dh/0
Genetic
Background
involves: C57BL/6J * C57BL/6N * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Ins2-Mirc13)E4Biat mutation (0 available)
Tg(RIP1-Tag)2Dh mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
N
• mice exhibit normal glucose serum levels after a 4 h fast unlike mice expressing the Mirc13 transgene alone

endocrine/exocrine glands
N
• mice exhibit normal beta cell mass unlike mice expressing the Mirc13 transgene alone




Genotype
MGI:6829614
tg5
Allelic
Composition
Tg(Ins2-Mirc13)E4Biat/0
Genetic
Background
C57BL/6N-Tg(Ins2-Mirc13)E4Biat
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• at 6 and 17 weeks of age
• severe

endocrine/exocrine glands
• at 6 and 17 weeks of age
• however, alpha cell mass is normal
• at 6 and 17 weeks of age

growth/size/body

adipose tissue

cellular





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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory