Phenotypes associated with this allele

• Allele Symbol: TgTn(pb-CAG-Gm40600)#Rew
• Allele Name: transgenic transposon concatemer, Renxi Wang
• Allele ID: MGI:6794092
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	TgTn(pb-CAG-Gm40600)#Rew/0	C57BL/6-TgTn(pb-CAG-Gm40600)#Rew	MGI:6798139

Genotype
MGI:6798139

tg1

• Allelic Composition: TgTn(pb-CAG-Gm40600)#Rew/0
• Genetic Background: C57BL/6-TgTn(pb-CAG-Gm40600)#Rew

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased B cell number ( J:311878 )

• reduced number of CD38-lo GL7-hi B220+ GC B cells after priming with NP-Ficoll

decreased plasma cell number ( J:311878 )

• reduced number of TAC1+ CD138+ B220- CD19-int early and TAC1+ CD138+ B220- CD19- mature PCs after priming with NP-Ficoll

increased B cell number ( J:311878 )

• CD38-lo GL7-hi B220+ CD19+ GC B cells after stimulation with sheep red blood cells (SRCs)

increased plasma cell number ( J:311878 )

• increased number of TAC1+ CD138+ B220- CD19-int early and TAC1+ CD138+ B220- CD19- mature PCs after stimulation with sheep red blood cells (SRCs)

abnormal plasmablast number ( J:311878 )

• reduced number of TAC1+ CD138+ B220-int CD19-int PBs after priming with NP-Ficoll

• increased number of TAC1+ CD138+ B220-int CD19-int PBs after stimulation with sheep red blood cells (SRCs)

decreased IgA level ( J:311878 )

• after priming with NP-Ficoll

increased IgA level ( J:311878 )

• after stimulation with sheep red blood cells (SRCs)

decreased IgE level ( J:311878 )

• after priming with NP-Ficoll

increased IgE level ( J:311878 )

• after stimulation with sheep red blood cells (SRCs)

decreased IgG level ( J:311878 )

• after priming with NP-Ficoll

decreased IgG1 level ( J:311878 )

• after priming with NP-Ficoll

decreased IgG2b level ( J:311878 )

• after priming with NP-Ficoll

decreased IgG2c level ( J:311878 )

• after priming with NP-Ficoll

decreased IgG3 level ( J:311878 )

• after priming with NP-Ficoll

increased IgG level ( J:311878 )

• after stimulation with sheep red blood cells (SRCs)

increased IgG1 level ( J:311878 )

• after stimulation with sheep red blood cells (SRCs)

increased IgG2b level ( J:311878 )

• after stimulation with sheep red blood cells (SRCs)

increased IgG2c level ( J:311878 )

• after stimulation with sheep red blood cells (SRCs)

increased IgG3 level ( J:311878 )

• after stimulation with sheep red blood cells (SRCs)

decreased IgM level ( J:311878 )

• after priming with NP-Ficoll

increased IgM level ( J:311878 )

• after stimulation with sheep red blood cells (SRCs)

hematopoietic system

decreased B cell number ( J:311878 )

• reduced number of CD38-lo GL7-hi B220+ GC B cells after priming with NP-Ficoll

decreased plasma cell number ( J:311878 )

• reduced number of TAC1+ CD138+ B220- CD19-int early and TAC1+ CD138+ B220- CD19- mature PCs after priming with NP-Ficoll

increased B cell number ( J:311878 )

• CD38-lo GL7-hi B220+ CD19+ GC B cells after stimulation with sheep red blood cells (SRCs)

increased plasma cell number ( J:311878 )

• increased number of TAC1+ CD138+ B220- CD19-int early and TAC1+ CD138+ B220- CD19- mature PCs after stimulation with sheep red blood cells (SRCs)

abnormal plasmablast number ( J:311878 )

• reduced number of TAC1+ CD138+ B220-int CD19-int PBs after priming with NP-Ficoll

• increased number of TAC1+ CD138+ B220-int CD19-int PBs after stimulation with sheep red blood cells (SRCs)

decreased IgA level ( J:311878 )

• after priming with NP-Ficoll

increased IgA level ( J:311878 )

• after stimulation with sheep red blood cells (SRCs)

decreased IgE level ( J:311878 )

• after priming with NP-Ficoll

increased IgE level ( J:311878 )

• after stimulation with sheep red blood cells (SRCs)

decreased IgG level ( J:311878 )

• after priming with NP-Ficoll

decreased IgG1 level ( J:311878 )

• after priming with NP-Ficoll

decreased IgG2b level ( J:311878 )

• after priming with NP-Ficoll

decreased IgG2c level ( J:311878 )

• after priming with NP-Ficoll

decreased IgG3 level ( J:311878 )

• after priming with NP-Ficoll

increased IgG level ( J:311878 )

• after stimulation with sheep red blood cells (SRCs)

increased IgG1 level ( J:311878 )

• after stimulation with sheep red blood cells (SRCs)

increased IgG2b level ( J:311878 )

• after stimulation with sheep red blood cells (SRCs)

increased IgG2c level ( J:311878 )

• after stimulation with sheep red blood cells (SRCs)

increased IgG3 level ( J:311878 )

• after stimulation with sheep red blood cells (SRCs)

decreased IgM level ( J:311878 )

• after priming with NP-Ficoll

increased IgM level ( J:311878 )

• after stimulation with sheep red blood cells (SRCs)