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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ercc6l2em2Mengf
endonuclease-mediated mutation 2, Feilong Meng
MGI:6792078
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ercc6l2em2Mengf/Ercc6l2em2Mengf Not Specified MGI:6792084


Genotype
MGI:6792084
hm1
Allelic
Composition		 Ercc6l2em2Mengf/Ercc6l2em2Mengf
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ercc6l2em2Mengf mutation (0 available); any Ercc6l2 mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal class switch recombination ( J:311900 )
• reduced ~50% in splenic B cells after stimulation with cytokines

immune system
immune system phenotype ( J:311900 )
N
• normal naive splenic B cell numbers
abnormal class switch recombination ( J:311900 )
• reduced ~50% in splenic B cells after stimulation with cytokines




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory