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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fbxo6tm1Yuyos
targeted mutation 1, Yukiko Yoshida
MGI:6758506
Summary 3 genotypes


Genotype
MGI:6758508
cx1
Allelic
Composition		 Fbxo2tm1Yuyos/Fbxo2tm1Yuyos
Fbxo6tm1Yuyos/Fbxo6tm1Yuyos
Genetic
Background		 B6.Cg-Fbxo6tm1Yuyos Fbxo2tm1Yuyos
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxo2tm1Yuyos mutation (0 available); any Fbxo2 mutation (23 available)
Fbxo6tm1Yuyos mutation (1 available); any Fbxo6 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:307684 )
• mice develop and breed normally




Genotype
MGI:6758510
cx2
Allelic
Composition		 Fbxo2tm1Yuyos/Fbxo2tm1Yuyos
Fbxo6tm1Yuyos/Fbxo6tm1Yuyos
Ngly1tm1.1Tasuz/Ngly1tm1.1Tasuz
Genetic
Background		 B6.Cg-Fbxo6tm1Yuyos Fbxo2tm1Yuyos Ngly1tm1.1Tasuz
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxo2tm1Yuyos mutation (0 available); any Fbxo2 mutation (23 available)
Fbxo6tm1Yuyos mutation (1 available); any Fbxo6 mutation (34 available)
Ngly1tm1.1Tasuz mutation (2 available); any Ngly1 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

nervous system
nervous system phenotype ( J:307684 )
N
• mice exhibit no pathological abnormality in the brain

behavior/neurological
behavior/neurological phenotype ( J:307684 )
N
• mice exhibit normal motor function




Genotype
MGI:6758511
cx3
Allelic
Composition		 Fbxo2tm1Yuyos/Fbxo2+
Fbxo6tm1Yuyos/Fbxo6+
Ngly1tm1.1Tasuz/Ngly1tm1.1Tasuz
Genetic
Background		 B6.Cg-Fbxo6tm1Yuyos Fbxo2tm1Yuyos Ngly1tm1.1Tasuz
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxo2tm1Yuyos mutation (0 available); any Fbxo2 mutation (23 available)
Fbxo6tm1Yuyos mutation (1 available); any Fbxo6 mutation (34 available)
Ngly1tm1.1Tasuz mutation (2 available); any Ngly1 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory