Fbxo6^tm1Yuyos
Targeted Allele Detail

Summary

• Symbol: Fbxo6^tm1Yuyos
• Name: F-box protein 6; targeted mutation 1, Yukiko Yoshida
• MGI ID: MGI:6758506
• Gene: Fbxo6 Location: Chr4:148230173-148236592 bp, - strand Genetic Position: Chr4, 78.67 cM
• Alliance: Fbxo6^tm1Yuyos page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:307684
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct replaced part of exon 1 and exons 2 to 4 with a neomycin resistance cassette with a 5' loxP site. (J:307684)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fbxo6 Mutation: 32 strains or lines available

Notes

This allele was generated in the same targeting event as Fbxo2^tm1Tasuz.

References

• Original: J:307684 Yoshida Y, et al., Loss of peptide:N-glycanase causes proteasome dysfunction mediated by a sugar-recognizing ubiquitin ligase. Proc Natl Acad Sci U S A. 2021 Jul 6;118(27):e2102902118
• All: 1 reference(s)