All Phenotypes Prxl2b<tm1.2Ksak> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Prxl2b^tm1.2Ksak
targeted mutation 1.2, Kenji Sakimura
MGI:6728799

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prxl2b^tm1.2Ksak/Prxl2b^tm1.2Ksak	involves: C57BL/6N * C57BL/6NCrlj * CBA/JNCrlj	MGI:6728801

Allelic Composition	Prxl2b^tm1.2Ksak/Prxl2b^tm1.2Ksak
Genetic Background	involves: C57BL/6N * C57BL/6NCrlj * CBA/JNCrlj

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prxl2b^tm1.2Ksak mutation (0 available); any Prxl2b mutation (20 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

ocular hypertension ( J:307536 )

• intraocular pressure is elevated by approximately 54 mmHg

homeostasis/metabolism

abnormal lipid level ( J:307536 )

• eye and gonadal white adipose tissue shows absence of prostamide F2alpha levels

• however, levels of anandamide, palmitoyl ethanolamide or oleoyl ethanolamdie are not affected

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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