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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fbxo10em2Ccg
endonuclease-mediated mutation 2, Christopher C Goodnow
MGI:6721015
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fbxo10em2Ccg/Fbxo10em2Ccg C57BL/6J-Fbxo10em2Ccg MGI:6721038


Genotype
MGI:6721038
hm1
Allelic
Composition		 Fbxo10em2Ccg/Fbxo10em2Ccg
Genetic
Background		 C57BL/6J-Fbxo10em2Ccg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxo10em2Ccg mutation (0 available); any Fbxo10 mutation (49 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:307413 )
• adults up to 50 weeks of age appear normal, healthy and have no differences in body weight, mice show no detectable defect in B cells in bone marrow or spleen, no effect on lymph node or spleen cellularity, no effect on the magnitude or quality of a polyclonal germ cell B cell response to sheep red blood cell immunization, no effect on T cell thymic development or T cell splenic maturation, and no effect on the distribution of murine lymphoid and myeloid leukocyte subsets in the bone marrow or spleen




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory