About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Del(8Ddx19a-Ddx19b)1Chaw
deletion, Chr 8, Changjiang Weng 1
MGI:6693696
Summary 2 genotypes


Genotype
MGI:6693796
hm1
Allelic
Composition		 Del(8Ddx19a-Ddx19b)1Chaw/Del(8Ddx19a-Ddx19b)1Chaw
Genetic
Background		 C57BL/6-Del(8Ddx19a-Ddx19b)1Chaw
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:6693797
ht2
Allelic
Composition		 Del(8Ddx19a-Ddx19b)1Chaw/+
Genetic
Background		 C57BL/6-Del(8Ddx19a-Ddx19b)1Chaw
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased interferon-alpha secretion ( J:289833 )
• by macrophages incubated with poly(I:C) or infected with Sendai virus (SeV)
increased interferon-beta secretion ( J:289833 )
• by macrophages incubated with poly(I:C) or infected with Sendai virus (SeV)
decreased susceptibility to Picornaviridae infection ( J:289833 )
• fewer copies of virus genome in mouse embryo fibroblasts (MEFs) infected with Encephalomyocarditis virus (EMCV)
decreased susceptibility to Picornaviridae infection induced morbidity/mortality ( J:289833 )
• significantly less pronounced damage to brain and heart after Encephalomyocarditis virus (EMCV) infection
• lower viral load in brain and heart after Encephalomyocarditis virus (EMCV) infection

growth/size/body
growth/size/body region phenotype ( J:289833 )
N
• no gross abnormalities

mortality/aging
mortality/aging ( J:289833 )
N
• viable
decreased susceptibility to Picornaviridae infection induced morbidity/mortality ( J:289833 )
• significantly less pronounced damage to brain and heart after Encephalomyocarditis virus (EMCV) infection
• lower viral load in brain and heart after Encephalomyocarditis virus (EMCV) infection

reproductive system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory