Phenotypes associated with this allele

• Allele Symbol: Cnot6l^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:6514804
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cnot6l^tm1b(EUCOMM)Wtsi/Cnot6l^tm1b(EUCOMM)Wtsi	C57BL/6NCrl-Cnot6l^tm1b(EUCOMM)Wtsi/Ieg	MGI:8298256

Genotype
MGI:8298256

hm1

• Allelic Composition: Cnot6l^{tm1b(EUCOMM)Wtsi}/Cnot6l^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6NCrl-Cnot6l^{tm1b(EUCOMM)Wtsi}/Ieg
• Cell Lines: EPD0802_1_H09

Data Sources

IMPC Data for Cnot6l

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased startle reflex ( J:211773 )

IMPC - HMGU

tremors ( J:211773 )

IMPC - HMGU

decreased locomotor activity ( J:211773 )

IMPC - HMGU

hyperactivity ( J:211773 )

IMPC - HMGU

increased vertical activity ( J:211773 )

IMPC - HMGU

cardiovascular system

increased heart weight ( J:211773 )

♂

IMPC - HMGU

thin ventricular wall ( J:211773 )

♂

IMPC - HMGU

growth/size/body

increased heart weight ( J:211773 )

♂

IMPC - HMGU

enlarged spleen ( J:211773 )

♂

IMPC - HMGU

hematopoietic system

enlarged spleen ( J:211773 )

♂

IMPC - HMGU

increased mean platelet volume ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - HMGU

immune system

enlarged spleen ( J:211773 )

♂

IMPC - HMGU

liver/biliary system

abnormal liver morphology ( J:211773 )

♂

IMPC - HMGU

nervous system

abnormal optic disk morphology ( J:211773 )

IMPC - HMGU

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - HMGU

vision/eye

abnormal optic disk morphology ( J:211773 )

IMPC - HMGU